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If, after one year of unprotected sex, a pregnancy has not occurred, this means that the man, woman, or both, may have a fertility problem. Poor production of sex hormones prevents the testicle from making sperm. Can be caused by:. Problems with ejaculation or an obstruction in the reproductive tract prevents sperm from being carried into the seminal fluid.

Defects in chromosomes the structure inside a cell nucleus that contains genetic material can affect the number, form, and size of sperm. Defects can occur at different locations on the Y male chromosome. In some cases, a piece of the Y chromosome may be missing microdeletion and cause infertility. Cleveland Clinic is a non-profit academic medical center.

Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Azoospermia Azoospermia is a lack of sperm in seminal fluid. How common is azoospermia? What are the types of azoospermia? The male reproductive system is made up of the following: Does this restaurant have tables with seating? Does this restaurant offer outdoor seating? Does this restaurant have waiters and waitresses? Is this restaurant good for lunch? Is this restaurant a hidden gem or off-the-beaten path?

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